WebJul 13, 2024 · Transiently dual CtBP1/2 knockdown had been achieved by a 48-h swap of CtBP1/2 siRNA interference in CtBP1/2 stable knockdown cancer cells, and validated by western blot analysis (Fig. 1B). WebC-terminal binding proteins (CtBP1/2) are transcriptional coregulators that play a significant role during vertebrate neurodevelopment. This systematic review aims to identify case reports with genetic variants in CTBP1 and CTBP2 associated with brain development …
CTBP1 antibody (10972-1-AP) Proteintech - ptglab
WebAug 14, 2024 · The phenotype of Ctbp1/2 DKO in ground-state ESCs resembles that of Klf2 KO ESCs cultured in 2i (Yeo et al., 2014). There was an abnormal upregulation of PGC markers in Klf2 KO ESCs under 2i conditions. In contrast, the expression of PGC-markers in Ctbp1/2 DKO ESCs were similar to those in wild-type ESCs under the 2i plus LIF … WebCTBP1-AS is an androgen-responsive lncRNA involved in the regulatory epigenetic network in prostate cancer, which functions in response to androgens [24]. Its expression is upregulated in prostate cancer, and it functions to stimulate cell proliferation both in cis - … on try on try是什么歌
Entry - *602618 - C-TERMINAL-BINDING PROTEIN 1; CTBP1 - OMIM
WebCTBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CTBP1 and the related protein CTBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and ... WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. Our RabMAb ® technology is a patented hybridoma-based technology ... The CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. CtBPs do this by recruiting histone modifying enzymes that add repressive histone marks and remove activating marks. CtBP proteins can also self-as… on ts018 elenco