WebAt stage one of DKD, you have mild kidney damage—such as protein in your urine or physical kidney damage—and an eGFR of 90 or higher. At this point, your kidneys are still working well, but—because DKD is progressive—your doctor might have you implement some lifestyle changes to slow down possible kidney damage. WebThe following sections of this consensus paper summarize key information from North American and European labels, clinical studies, and guidelines for each of the major antihyperglycemic medications, relevant to the treatment of adults with T2DM and CKD. Metformin must be avoided when the eGFR <30 ml/min/1.73 m2.
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WebDec 5, 2024 · Renal Dose Adjustments. Mild renal impairment (eGFR 45 mL/min/1.73 m2 or greater): No adjustment recommended. Moderate renal impairment (eGFR 30 … WebIndications and Dosage. Adult: As conventional tab: Initially, 40-80 mg daily; may increase as necessary until adequate control is achieved. Max: 320 mg daily. Doses >160 mg daily are given in 2 divided doses. As modified-release tab: Initially, 30 mg daily; may increase in increments of 30 mg at intervals of at least 1 month (or after 2 weeks ... daily nucleic acid testing
Pharmacologic Glycemic Management of Type 2 Diabetes …
WebMar 30, 2024 · In patients with an eGFR between 30 and 60 mL/min/1.73 m2; In patients with a history of hepatic impairment, alcoholism, or heart failure; In patients receiving intra-arterial iodinated contrast; Re-evaluate eGFR 48 hours after procedure; restart therapy only if renal function is stable. Concomitant use with Insulin or Insulin Secretagogues: Web• Gliclazide (Diamicron & generics) 80 mg modified release (MR) 30 mg • Glimepiride (Amaryl & generics) 1 mg, 2 mg, 4 mg • Glyburide (Diabeta & generics) 2.5, 5 mg • Repaglinide (Gluconorm & generics) 0.5 mg, 1 mg, 2 mg • Nateglinide (Starlix) 60, 120, 180 mg • Pioglitazone (Actos & generics) 15, 30, 45 mg Web25 mg; 1 tablet, once daily. Tablets not shown at actual size. eGFR = estimated glomerular filtration rate. There have been postmarketing reports of worsening renal function, including acute renal failure, sometimes requiring dialysis. A subset of these reports involved patients with renal impairment, some of whom were prescribed inappropriate ... daily nuggets meaning